HMGN1P35

Across TCGA pan-cancer cohorts, HMGN1P35 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated HMGN1P35 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher HMGN1P35 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN1P35 expression acts as an unfavorable survival marker, although some lineages such as BLCA and ESCA show a favorable association.

PAAD, BLCA, and UVM are the cancer types where HMGN1P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Quartile	All	0.324	0.547	.001	39	view →
BLCA	OS	Quartile	IV	0.510	0.183	.010	33	view →
UVM	DFS	Quartile	All	0.116	0.816	.001	27	view →
ESCA	DFS	Quartile	II,III,IV	0.633	0.383	.004	24	view →
SKCM	OS	Tertile	All	0.852	0.740	.002	18	view →
KICH	OS	Median	II,III,IV	0.520	1.000	.008	17	view →
SARC	OS	Tertile	All	0.352	0.616	.004	12	view →
UCS	DFS	Tertile	IV	0.860	0.364	.024	12	view →
LGG	DFS	Tertile	All	0.679	0.786	.010	11	view →
KIRP	DFS	Tertile	All	0.886	0.955	.014	10	view →
DLBC	DFS	Quartile	All	1.000	0.546	.003	9	view →
COAD	DFS	Quartile	IV	0.204	0.594	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

HMGN1P35–PAAD (DFS)

Open the PAAD breakdown →