HMGN1P31

Across TCGA pan-cancer cohorts, HMGN1P31 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated HMGN1P31 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher HMGN1P31 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGN1P31 expression acts as an unfavorable survival marker.

THCA, LIHC, and KIRP are the cancer types where HMGN1P31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.549	0.875	<.001	99	view →
LIHC	OS	Tertile	All	0.150	0.709	<.001	72	view →
KIRP	DFS	Tertile	II,III,IV	0.169	0.693	.007	42	view →
SKCM	DFS	Tertile	III,IV	0.190	0.620	<.001	30	view →
LUAD	OS	Tertile	All	0.330	0.700	.010	27	view →
DLBC	DFS	Tertile	All	0.416	0.829	.026	18	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →
ACC	DFS	Tertile	All	0.089	0.666	.017	18	view →
UCEC	DFS	Tertile	IV	0.181	0.705	.009	18	view →
STAD	OS	Tertile	II,III,IV	0.497	0.720	.039	9	view →
LGG	OS	Tertile	All	0.197	0.525	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

HMGN1P31–THCA (OS)

Open the THCA breakdown →