HMGN1P30

Across TCGA patient cohorts, HMGN1P30 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,936 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGN1P30-associated GO terms across cancer lineages are Maturation of 5.8S rRNA, rRNA metabolic process, and RNA 3'-end processing. Each is linked with HMGN1P30 in more than 21 cancer types. Because this analysis shows association rather than direction, both HMGN1P30-to-partner and partner-to-HMGN1P30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA grouped by HMGN1P30-low versus HMGN1P30-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P30→partner) and Y-score (partner→HMGN1P30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Maturation of 5.8S rRNA →	+0.053	+0.205	<.001	<.001	3	22
STAD	rRNA metabolic process →	+0.047	+0.194	<.001	<.001	3	21
LAML	RNA 3'-end processing →	+0.045	+0.472	<.001	<.001	3	21
STAD	Methylation →	+0.037	+0.225	<.001	<.001	3	21
STAD	Macromolecule methylation →	+0.037	+0.200	<.001	<.001	3	21
STAD	Positive regulation of chromosome organization →	+0.043	+0.170	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,936 associations by consensus.

Maturation of 5.8S rRNA by HMGN1P30 expression — STAD

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