HMGN1P28

Across TCGA patient cohorts, HMGN1P28 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,623 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGN1P28-associated GO terms across cancer lineages are Regulation of organelle assembly, DNA-templated transcription elongation, and Macromolecule methylation. Each is linked with HMGN1P28 in more than 21 cancer types. Because this analysis shows association rather than direction, both HMGN1P28-to-partner and partner-to-HMGN1P28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by HMGN1P28-low versus HMGN1P28-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P28→partner) and Y-score (partner→HMGN1P28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of organelle assembly →	+0.067	+0.333	<.001	<.001	3	22
STAD	DNA-templated transcription elongation →	+0.060	+0.268	<.001	<.001	3	22
STAD	Macromolecule methylation →	+0.050	+0.245	<.001	<.001	3	22
STAD	RNA localization →	+0.059	+0.229	<.001	<.001	3	22
STAD	RNA modification →	+0.051	+0.267	<.001	<.001	3	21
STAD	Positive regulation of DNA-templated transcription, elongation →	+0.058	+0.234	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,623 associations by consensus.

Regulation of organelle assembly by HMGN1P28 expression — ESCA

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