HMGN1P26

Across TCGA pan-cancer cohorts, HMGN1P26 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated HMGN1P26 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HMGN1P26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGN1P26 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUSC show a favorable association.

COAD, UVM, and BRCA are the cancer types where HMGN1P26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.175	0.727	<.001	60	view →
UVM	OS	Tertile	All	0.213	0.696	.004	45	view →
BRCA	DFS	Tertile	III,IV	0.761	0.378	<.001	43	view →
PAAD	OS	Tertile	All	0.403	0.684	.002	36	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	36	view →
KIRP	DFS	Tertile	IV	0.154	0.548	<.001	36	view →
ACC	OS	Tertile	II,III,IV	0.224	0.764	.003	31	view →
DLBC	OS	Tertile	All	0.060	0.836	<.001	27	view →
STAD	DFS	Tertile	All	0.383	0.655	.015	27	view →
MESO	OS	Quartile	II,III,IV	0.358	0.627	.001	20	view →
SKCM	DFS	Tertile	IV	0.038	0.477	.001	18	view →
LUAD	DFS	Tertile	IV	0.416	0.756	.021	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

HMGN1P26–COAD (OS)

Open the COAD breakdown →