HMGN1P17

Across TCGA patient cohorts, HMGN1P17 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,818 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HMGN1P17-associated GO terms across cancer lineages are Regulation of binding, Negative regulation of transferase activity, and Negative regulation of protein serine/threonine kinase activity. Each is linked with HMGN1P17 in more than 15 cancer types. Because this analysis shows association rather than direction, both HMGN1P17-to-partner and partner-to-HMGN1P17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of binding grouped by HMGN1P17-low versus HMGN1P17-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P17→partner) and Y-score (partner→HMGN1P17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of binding →	+0.064	+0.351	<.001	<.001	3	15
ESCA	Negative regulation of transferase activity →	+0.066	+0.432	<.001	<.001	3	15
ESCA	Negative regulation of protein serine/threonine kinase activity →	+0.060	+0.204	<.001	.001	3	15
ESCA	Pyrimidine-containing compound metabolic process →	+0.045	+0.212	<.001	.001	2	16
ESCA	Positive regulation of type I interferon production →	+0.067	+0.195	<.001	.002	2	16
STAD	Cellular response to oxidative stress →	+0.070	+0.280	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,818 associations by consensus.

Regulation of binding by HMGN1P17 expression — ESCA

Explore this box plot interactively →