HMGN1P15

Across TCGA patient cohorts, HMGN1P15 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGN1P15-associated proteins across cancer lineages are PTPN14_S620, ARID4B_S675, and PRPF31. Each is linked with HMGN1P15 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGN1P15-to-partner and partner-to-HMGN1P15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGN1P15 versus PTPN14_S620 in GBM, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P15→partner) and Y-score (partner→HMGN1P15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN14_S620 →	-0.480	-0.385	.002	.002	3	3
GBM	ARID4B_S675 →	+0.651	+0.528	<.001	.001	3	3
GBM	PRPF31 →	+0.280	+0.493	.001	<.001	3	3
LSCC	PWP1 →	+0.218	+0.578	.003	.001	3	3
GBM	S100A8 →	-1.044	-0.379	<.001	<.001	3	3
GBM	GTF3C3 →	+0.248	+0.432	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,020 associations by consensus.

HMGN1P15 vs PTPN14_S620 — GBM

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