HMGN1P12

Across TCGA pan-cancer cohorts, HMGN1P12 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HMGN1P12’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where HMGN1P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN1P12 is over-expressed in tumor.

BRCA, STAD, and KIRC are the cancer types where HMGN1P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN1P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.199	.021	4	view →
STAD	Male	II,III,IV	+0.252	.049	1	view →
KIRC	All	All	+0.073	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

HMGN1P12–BRCA

Open the BRCA breakdown →