Across TCGA patient cohorts, HMGN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,008 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGN1-associated proteins across cancer lineages are GART, SCAF4, and SON. Each is linked with HMGN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGN1-to-partner and partner-to-HMGN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1→partner) and Y-score (partner→HMGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GART →	+0.445	+0.555	<.001	<.001	3	7
LSCC	SCAF4 →	+0.337	+0.495	.001	.002	3	6
GBM	SON →	+0.266	+0.474	<.001	.001	3	5
COAD	KIF2C →	+0.616	+0.504	<.001	<.001	3	5
GBM	MCM5 →	+0.658	+0.360	<.001	<.001	3	5
OV	MORC3 →	+0.259	+0.566	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,008 associations by consensus.

Exploration

HMGN1 survival (RNA) · tumor vs normal (RNA) · all HMGN1 data types