HMGN1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HMGN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,365 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HMGN1-associated GO terms across cancer lineages are Regulation of metaphase/anaphase transition of cell cycle, Regulation of mitotic metaphase/anaphase transition, and Regulation of sister chromatid segregation. Each is linked with HMGN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HMGN1-to-partner and partner-to-HMGN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1→partner) and Y-score (partner→HMGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRegulation of metaphase/anaphase transition of cell cycle →+0.115+1.019<.001<.001316
BLOOD_LymphomaRegulation of mitotic metaphase/anaphase transition →+0.116+1.093<.001<.001316
BLOOD_LymphomaRegulation of sister chromatid segregation →+0.117+1.077<.001<.001316
BLOOD_MyelomaDNA-templated DNA replication maintenance of fidelity →+0.112+0.778<.001<.001316
BLOOD_MyelomaDNA replication →+0.111+0.892<.001<.001316
BLOOD_LymphomaDNA-templated DNA replication →+0.105+1.288<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,365 associations by consensus.

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