HMGB3P5

Across TCGA patient cohorts, HMGB3P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,672 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P5-associated GO terms across cancer lineages are Telomerase RNA localization, NADH dehydrogenase complex assembly, and Nucleoside phosphate biosynthetic process. Each is linked with HMGB3P5 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMGB3P5-to-partner and partner-to-HMGB3P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase RNA localization grouped by HMGB3P5-low versus HMGB3P5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P5→partner) and Y-score (partner→HMGB3P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Telomerase RNA localization →	+0.064	+0.458	.002	<.001	3	12
STAD	NADH dehydrogenase complex assembly →	+0.066	+0.473	<.001	<.001	3	12
STAD	Nucleoside phosphate biosynthetic process →	+0.054	+0.433	<.001	<.001	3	12
STAD	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.070	+0.398	<.001	<.001	3	12
ESCA	Regulation of telomere maintenance in response to DNA damage →	+0.057	+0.386	<.001	<.001	3	11
ESCA	Positive regulation of telomerase activity →	+0.074	+0.464	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,672 associations by consensus.

Telomerase RNA localization by HMGB3P5 expression — ESCA

Explore this box plot interactively →