HMGB3P3

Across TCGA patient cohorts, HMGB3P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,355 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P3-associated GO terms across cancer lineages are Regulation of binding, Obsolete ncRNA transcription, and Protein polymerization. Each is linked with HMGB3P3 in more than 12 cancer types. Because this analysis shows association rather than direction, both HMGB3P3-to-partner and partner-to-HMGB3P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of binding grouped by HMGB3P3-low versus HMGB3P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P3→partner) and Y-score (partner→HMGB3P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of binding →	+0.063	+0.269	<.001	<.001	3	13
STAD	Obsolete ncRNA transcription →	+0.064	+0.271	<.001	<.001	3	12
STAD	Protein polymerization →	+0.063	+0.264	<.001	<.001	3	12
STAD	Protein folding →	+0.070	+0.259	<.001	<.001	3	12
STAD	Protein polyubiquitination →	+0.070	+0.261	<.001	<.001	3	11
STAD	Negative regulation of cellular catabolic process →	+0.064	+0.289	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,355 associations by consensus.

Regulation of binding by HMGB3P3 expression — STAD

Explore this box plot interactively →