HMGB3P26

Across TCGA patient cohorts, HMGB3P26 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,130 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P26-associated GO terms across cancer lineages are Negative regulation of DNA metabolic process, Negative regulation of transferase activity, and Regulation of reproductive process. Each is linked with HMGB3P26 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGB3P26-to-partner and partner-to-HMGB3P26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA metabolic process grouped by HMGB3P26-low versus HMGB3P26-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P26→partner) and Y-score (partner→HMGB3P26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA metabolic process →	+0.068	+0.137	<.001	<.001	3	7
STAD	Negative regulation of transferase activity →	+0.072	+0.138	<.001	<.001	3	6
STAD	Regulation of reproductive process →	+0.042	+0.123	<.001	<.001	3	6
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.092	+0.148	<.001	<.001	3	6
STAD	Negative regulation of protein ubiquitination →	+0.075	+0.147	<.001	<.001	3	6
STAD	Ribosome assembly →	+0.089	+0.161	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,130 associations by consensus.

Negative regulation of DNA metabolic process by HMGB3P26 expression — STAD

Explore this box plot interactively →