Across TCGA patient cohorts, HMGB3P21 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB3P21-associated proteins across cancer lineages are ZMYM3, THOC2_T1443, and TAX1BP3. Each is linked with HMGB3P21 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB3P21-to-partner and partner-to-HMGB3P21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P21→partner) and Y-score (partner→HMGB3P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZMYM3 →	+0.281	+0.756	<.001	.001	3	4
PDAC	THOC2_T1443 →	+0.442	+0.359	<.001	.003	3	4
HNSC	TAX1BP3 →	-0.219	-0.516	<.001	.008	3	4
LSCC	BPTF_S216 →	+0.438	+0.621	<.001	<.001	3	4
GBM	BUD31 →	+0.363	+0.456	.002	.009	3	4
LSCC	GTF2I →	+0.397	+0.499	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,945 associations by consensus.

Exploration

HMGB3P21 survival (RNA) · tumor vs normal (RNA) · all HMGB3P21 data types