Across TCGA patient cohorts, HMGB3P21 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,649 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P21-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, DNA-templated transcription termination, and Peptidyl-lysine methylation. Each is linked with HMGB3P21 in more than 16 cancer types. Because this analysis shows association rather than direction, both HMGB3P21-to-partner and partner-to-HMGB3P21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P21→partner) and Y-score (partner→HMGB3P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of gene expression, epigenetic →	+0.053	+0.205	<.001	<.001	3	17
STAD	DNA-templated transcription termination →	+0.054	+0.219	<.001	<.001	3	17
STAD	Peptidyl-lysine methylation →	+0.047	+0.214	<.001	<.001	3	16
STAD	Protein polyubiquitination →	+0.058	+0.212	<.001	<.001	3	16
STAD	RNA 3'-end processing →	+0.057	+0.225	<.001	<.001	3	16
STAD	Positive regulation of telomere maintenance →	+0.057	+0.212	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,649 associations by consensus.

Exploration

HMGB3P21 survival (RNA) · tumor vs normal (RNA) · all HMGB3P21 data types