HMGB3P15

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, HMGB3P15 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of HMGB3P15’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where HMGB3P15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGB3P15 is over-expressed in tumor.

PRAD and COAD are the cancer types where HMGB3P15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGB3P15 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
PRADAllAll+0.015.0322view →
COADAllAll+0.015.0441view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

HMGB3P15–PRAD

Tumor-vs-normal expression box plot for HMGB3P15 RNA in PRAD.

Open the PRAD breakdown →

Exploration