Across TCGA pan-cancer cohorts, HMGB3P10 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated HMGB3P10 data layer.
The strongest signal is observed in rectum adenocarcinoma (READ), where higher HMGB3P10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGB3P10 expression acts as an unfavorable survival marker, although some lineages such as MESO and UCS show a favorable association.
READ, LGG, and MESO are the cancer types where HMGB3P10 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.