Across TCGA patient cohorts, HMGB3P1 mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMGB3P1-associated genes across cancer lineages are NDUFA4P2, RNU6-824P, and HSPE1-MOB4. Each is linked with HMGB3P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMGB3P1-to-partner and partner-to-HMGB3P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P1→partner) and Y-score (partner→HMGB3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NDUFA4P2 →	+0.237	+5.622	<.001	<.001	3	2
UCEC	RNU6-824P →	+0.637	+3.022	.001	.001	3	2
UCEC	HSPE1-MOB4 →	+0.225	+3.021	<.001	.004	3	1
UCEC	BNIP3P4 →	+0.110	+3.899	<.001	<.001	3	1
UCEC	IGHV1OR15-3 →	+0.124	+3.092	.003	.003	3	1
UCEC	TBC1D3L →	+0.686	+3.304	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

Exploration

HMGB3P1 survival (RNA) · tumor vs normal (RNA) · all HMGB3P1 data types