Across TCGA patient cohorts, HMGB3P1 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMGB3P1-associated genes across cancer lineages are JNK2, NDRG1_pT346, and SETD2. Each is linked with HMGB3P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMGB3P1-to-partner and partner-to-HMGB3P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P1→partner) and Y-score (partner→HMGB3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.275	+3.000	.016	.037	3	1
UCEC	NDRG1_pT346 →	-0.568	-3.000	.044	.037	3	1
UCEC	SETD2 →	-0.249	-3.000	.048	.037	3	1
UCEC	beta-Catenin →	+0.591	+3.000	.043	.037	3	1
UCEC	14-3-3_beta →	-0.143	-2.986	.014	.037	1	1
UCEC	Chk2_pT68 →	-0.213	-3.000	.048	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

HMGB3P1 survival (RNA) · tumor vs normal (RNA) · all HMGB3P1 data types