HMGB1P8

Across TCGA patient cohorts, HMGB1P8 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,259 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HMGB1P8-associated proteins across cancer lineages are STX12_S139, TOP1_S112, and UGDH_S476. Each is linked with HMGB1P8 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P8-to-partner and partner-to-HMGB1P8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P8 versus STX12_S139 in OV, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P8→partner) and Y-score (partner→HMGB1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	STX12_S139 →	-1.466	-0.667	<.001	.001	3	3
OV	TOP1_S112 →	-1.111	-0.690	.001	.002	3	3
HNSC	UGDH_S476 →	+1.024	+0.761	.001	.005	3	3
HNSC	MYH11_S638 →	+1.026	+0.753	.003	.001	3	3
HNSC	MYH11_S645 →	+1.026	+0.753	.003	.001	3	3
GBM	ARHGEF2 →	+0.267	+0.417	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,259 associations by consensus.

HMGB1P8 vs STX12_S139 — OV

Explore this scatter interactively →