HMGB1P6

Across TCGA patient cohorts, HMGB1P6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,164 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGB1P6-associated proteins across cancer lineages are HMGB1, NCAPG, and NCAPH. Each is linked with HMGB1P6 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGB1P6-to-partner and partner-to-HMGB1P6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P6 versus HMGB1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P6→partner) and Y-score (partner→HMGB1P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HMGB1 →	+0.381	+0.814	<.001	<.001	3	7
BRCA	NCAPG →	+0.498	+0.778	<.001	<.001	3	6
BRCA	NCAPH →	+0.547	+0.826	<.001	<.001	3	6
UCEC	UHRF1 →	+0.746	+0.605	<.001	<.001	3	6
LSCC	SMARCA5 →	+0.288	+0.618	<.001	<.001	3	6
LSCC	POLD3 →	+0.454	+0.544	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,164 associations by consensus.

HMGB1P6 vs HMGB1 — BRCA

Explore this scatter interactively →