HMGB1P48

Across TCGA patient cohorts, HMGB1P48 RNA expression is significantly associated with the protein abundance of many other proteins, with 1,659 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HMGB1P48-associated proteins across cancer lineages are CBY1, EIF4E3, and WASHC2C_S663. Each is linked with HMGB1P48 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMGB1P48-to-partner and partner-to-HMGB1P48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P48 versus CBY1 in PDAC, with a Pearson correlation of -0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P48→partner) and Y-score (partner→HMGB1P48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CBY1 →	-0.717	-0.222	<.001	.004	3	2
CCRCC	EIF4E3 →	-0.189	-0.089	.009	.006	3	2
LUAD	WASHC2C_S663 →	+0.410	+0.065	.009	.007	3	2
UCEC	SLC5A3_S559 →	+0.972	+0.192	<.001	.008	3	2
HNSC	TMPO_S214 →	+1.213	+0.150	.001	.006	3	1
PDAC	RRAGD_T391 →	+0.291	+0.100	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,659 associations by consensus.

HMGB1P48 vs CBY1 — PDAC

Explore this scatter interactively →