HMGB1P47

Across TCGA pan-cancer cohorts, HMGB1P47 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of HMGB1P47’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where HMGB1P47 RNA is repressed in tumor relative to normal tissue. In most cancer types HMGB1P47 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

STAD are the cancer types where HMGB1P47 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGB1P47 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	−0.159	.016	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

HMGB1P47–STAD

Open the STAD breakdown →