HMGB1P46

Across TCGA patient cohorts, HMGB1P46 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,316 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P46-associated GO terms across cancer lineages are Protein folding, Neural tube development, and Cellular respiration. Each is linked with HMGB1P46 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMGB1P46-to-partner and partner-to-HMGB1P46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by HMGB1P46-low versus HMGB1P46-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P46→partner) and Y-score (partner→HMGB1P46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Protein folding →	+0.057	+0.011	<.001	.001	3	12
ESCA	Neural tube development →	+0.042	+0.178	<.001	.001	3	12
STAD	Cellular respiration →	+0.059	+0.050	<.001	<.001	3	12
STAD	Double-strand break repair via nonhomologous end joining →	+0.052	+0.056	<.001	<.001	3	11
STAD	RNA localization →	+0.067	+0.055	<.001	<.001	3	11
STAD	tRNA processing →	+0.052	+0.057	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,316 associations by consensus.

Protein folding by HMGB1P46 expression — KIRP

Explore this box plot interactively →