HMGB1P42

Across TCGA patient cohorts, HMGB1P42 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,220 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGB1P42-associated proteins across cancer lineages are SOS1_S1167, UBL4A_S90, and PRRC2C_S1502. Each is linked with HMGB1P42 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P42-to-partner and partner-to-HMGB1P42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P42 versus SOS1_S1167 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P42→partner) and Y-score (partner→HMGB1P42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOS1_S1167 →	+0.566	+0.357	.006	.001	3	3
GBM	UBL4A_S90 →	+0.452	+0.335	.001	.001	3	2
GBM	PRRC2C_S1502 →	-0.797	-0.452	<.001	<.001	3	2
GBM	RPL18A_S123 →	-0.581	-0.381	.001	.002	3	2
GBM	JADE3 →	+0.358	+0.414	.006	<.001	3	2
GBM	LYN_S11 →	-0.916	-0.577	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,220 associations by consensus.

HMGB1P42 vs SOS1_S1167 — GBM

Explore this scatter interactively →