Across TCGA patient cohorts, HMGB1P39 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,780 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P39-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, tRNA modification, and Histone mRNA metabolic process. Each is linked with HMGB1P39 in more than 19 cancer types. Because this analysis shows association rather than direction, both HMGB1P39-to-partner and partner-to-HMGB1P39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P39→partner) and Y-score (partner→HMGB1P39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.052	+0.153	<.001	<.001	3	20
STAD	tRNA modification →	+0.052	+0.179	<.001	<.001	3	20
STAD	Histone mRNA metabolic process →	+0.050	+0.185	<.001	<.001	3	19
STAD	Protein neddylation →	+0.068	+0.221	<.001	<.001	3	19
STAD	Microtubule polymerization →	+0.057	+0.223	<.001	<.001	3	19
ESCA	RNA destabilization →	+0.058	+0.234	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,780 associations by consensus.

Exploration

HMGB1P39 survival (RNA) · tumor vs normal (RNA) · all HMGB1P39 data types