Across TCGA patient cohorts, HMGB1P37 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,252 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGB1P37-associated proteins across cancer lineages are PTK6, XRN2_S448, and CDS2_S33. Each is linked with HMGB1P37 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P37-to-partner and partner-to-HMGB1P37 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P37→partner) and Y-score (partner→HMGB1P37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTK6 →	-0.549	-1.288	.001	<.001	3	3
OV	XRN2_S448 →	+0.702	+1.912	<.001	<.001	3	3
UCEC	CDS2_S33 →	+0.876	+0.716	<.001	<.001	3	3
OV	CETN2_S20 →	-0.646	-1.370	<.001	.002	3	3
OV	REEP3_S210 →	-0.619	-1.788	.002	.002	3	2
OV	RELCH_S244 →	-0.944	-1.985	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,252 associations by consensus.

Exploration

HMGB1P37 survival (RNA) · tumor vs normal (RNA) · all HMGB1P37 data types