HMGB1P35

Across TCGA patient cohorts, HMGB1P35 RNA expression is significantly associated with the RNA expression of many other genes, with 5,194 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible HMGB1P35-associated genes across cancer lineages are ZBED3-AS1, SEMA6A-AS1, and PNISR. Each is linked with HMGB1P35 in more than 18 cancer types. Because this analysis shows association rather than direction, both HMGB1P35-to-partner and partner-to-HMGB1P35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P35 versus ZBED3-AS1 in SKCM, with a Pearson correlation of 0.43.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P35→partner) and Y-score (partner→HMGB1P35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZBED3-AS1 →	+0.725	+0.048	<.001	<.001	3	19
UVM	SEMA6A-AS1 →	+0.699	+0.065	.004	.005	1	19
UVM	PNISR →	+1.221	+0.042	.001	.007	2	18
UCS	ZNF32-AS2 →	+0.808	+0.085	.003	<.001	3	17
KIRP	CROCCP3 →	+0.624	+0.038	<.001	<.001	3	17
UVM	NBPF11 →	+0.691	+0.074	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,194 associations by consensus.

HMGB1P35 vs ZBED3-AS1 — SKCM

Explore this scatter interactively →