Across TCGA patient cohorts, HMGB1P32 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,070 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P32-associated GO terms across cancer lineages are Regulation of cyclin-dependent protein kinase activity, rRNA methylation, and Seminiferous tubule development. Each is linked with HMGB1P32 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGB1P32-to-partner and partner-to-HMGB1P32 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P32→partner) and Y-score (partner→HMGB1P32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.078	+0.137	<.001	<.001	3	8
STAD	rRNA methylation →	+0.077	+0.143	<.001	<.001	3	7
STAD	Seminiferous tubule development →	+0.065	+0.122	<.001	<.001	3	7
STAD	Male sex differentiation →	+0.063	+0.128	<.001	<.001	3	7
STAD	Negative regulation of centrosome duplication →	+0.075	+0.131	<.001	<.001	3	6
STAD	sno(s)RNA metabolic process →	+0.070	+0.138	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,070 associations by consensus.

Exploration

HMGB1P32 survival (RNA) · tumor vs normal (RNA) · all HMGB1P32 data types