HMGB1P31

Across TCGA patient cohorts, HMGB1P31 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,200 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGB1P31-associated proteins across cancer lineages are SS18, LYAR_S260, and ARHGEF2_T679. Each is linked with HMGB1P31 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB1P31-to-partner and partner-to-HMGB1P31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P31 versus SS18 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P31→partner) and Y-score (partner→HMGB1P31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SS18 →	+0.374	+0.326	<.001	.004	3	4
HNSC	LYAR_S260 →	-0.587	-0.533	<.001	.008	3	4
CCRCC	ARHGEF2_T679 →	-0.393	-0.258	.002	.003	3	3
GBM	TERF2 →	+0.306	+0.385	<.001	<.001	3	3
UCEC	ATP13A3 →	-0.308	-1.035	<.001	<.001	3	3
PDAC	CHPF2 →	-0.445	-0.466	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,200 associations by consensus.

HMGB1P31 vs SS18 — PDAC

Explore this scatter interactively →