HMGB1P3

Across TCGA patient cohorts, HMGB1P3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,052 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P3-associated proteins across cancer lineages are OASL, LGALS9, and APOL3. Each is linked with HMGB1P3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMGB1P3-to-partner and partner-to-HMGB1P3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P3 versus OASL in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P3→partner) and Y-score (partner→HMGB1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OASL →	+0.735	+0.501	<.001	.005	3	6
GBM	LGALS9 →	+0.417	+0.464	.002	<.001	3	6
HNSC	APOL3 →	+0.660	+0.498	<.001	.005	3	5
HNSC	MX2 →	+0.784	+0.648	.001	.002	3	5
HNSC	OAS2 →	+0.711	+0.587	<.001	.001	3	5
HNSC	OAS3 →	+0.622	+0.768	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,052 associations by consensus.

HMGB1P3 vs OASL — HNSC

Explore this scatter interactively →