HMGB1P24

Across TCGA patient cohorts, HMGB1P24 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,555 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P24-associated proteins across cancer lineages are ACACA_S80, UTP25, and IWS1. Each is linked with HMGB1P24 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMGB1P24-to-partner and partner-to-HMGB1P24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P24 versus ACACA_S80 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P24→partner) and Y-score (partner→HMGB1P24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ACACA_S80 →	+0.625	+0.818	<.001	<.001	3	6
LSCC	UTP25 →	+0.367	+0.565	<.001	<.001	3	5
GBM	IWS1 →	+0.263	+0.439	.002	<.001	3	5
HNSC	ACACA →	+0.490	+0.878	<.001	<.001	3	5
LSCC	AATF →	+0.377	+0.658	<.001	<.001	3	5
LSCC	THOC1 →	+0.267	+0.638	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,555 associations by consensus.

HMGB1P24 vs ACACA_S80 — HNSC

Explore this scatter interactively →