HMGB1P18

Across TCGA patient cohorts, HMGB1P18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,073 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P18-associated GO terms across cancer lineages are snRNA processing, Positive regulation of intracellular protein transport, and snRNA metabolic process. Each is linked with HMGB1P18 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMGB1P18-to-partner and partner-to-HMGB1P18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA processing grouped by HMGB1P18-low versus HMGB1P18-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P18→partner) and Y-score (partner→HMGB1P18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	snRNA processing →	+0.063	+0.112	<.001	<.001	3	12
STAD	Positive regulation of intracellular protein transport →	+0.065	+0.106	<.001	<.001	3	11
KIRP	snRNA metabolic process →	+0.066	+0.044	<.001	<.001	3	11
KIRP	Establishment of RNA localization →	+0.077	+0.055	<.001	<.001	3	11
KIRP	Regulation of mRNA catabolic process →	+0.056	+0.042	<.001	<.001	3	11
STAD	Signal transduction by p53 class mediator →	+0.062	+0.107	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,073 associations by consensus.

snRNA processing by HMGB1P18 expression — STAD

Explore this box plot interactively →