Across TCGA patient cohorts, HMGB1P16 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,853 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HMGB1P16-associated proteins across cancer lineages are SPA17, TTC25, and MLF1_S34. Each is linked with HMGB1P16 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB1P16-to-partner and partner-to-HMGB1P16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P16→partner) and Y-score (partner→HMGB1P16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPA17 →	+1.160	+1.215	<.001	<.001	3	4
UCEC	TTC25 →	+0.725	+1.289	<.001	<.001	3	4
LSCC	MLF1_S34 →	+0.700	+0.616	.009	.009	3	4
LUAD	C7orf57_S209 →	+1.448	+0.776	<.001	<.001	3	4
UCEC	C7orf57_S250 →	+1.262	+1.871	<.001	<.001	3	4
UCEC	TSGA10 →	+0.813	+1.361	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,853 associations by consensus.

Exploration

HMGB1P16 survival (RNA) · tumor vs normal (RNA) · all HMGB1P16 data types