HMGB1P11

Across TCGA patient cohorts, HMGB1P11 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,768 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P11-associated proteins across cancer lineages are IRF2BP2, ZNF638, and DNMT3A. Each is linked with HMGB1P11 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB1P11-to-partner and partner-to-HMGB1P11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P11 versus IRF2BP2 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P11→partner) and Y-score (partner→HMGB1P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IRF2BP2 →	+0.318	+0.496	.002	<.001	3	4
LSCC	ZNF638 →	+0.197	+0.313	<.001	.003	3	3
OV	DNMT3A →	+0.764	+0.471	<.001	<.001	3	3
OV	GTF3C2 →	+0.349	+0.480	<.001	.002	3	3
OV	ATXN2L →	+0.325	+0.477	<.001	<.001	3	3
OV	CDK9 →	+0.298	+0.355	.005	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,768 associations by consensus.

HMGB1P11 vs IRF2BP2 — OV

Explore this scatter interactively →