Across TCGA patient cohorts, HMGB1P10 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,557 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P10-associated proteins across cancer lineages are NUP153, NUP153_S687, and PPP3CA_S492. Each is linked with HMGB1P10 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB1P10-to-partner and partner-to-HMGB1P10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P10→partner) and Y-score (partner→HMGB1P10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUP153 →	+0.367	+1.540	<.001	<.001	3	4
OV	NUP153_S687 →	+1.637	+2.711	<.001	<.001	3	4
BRCA	PPP3CA_S492 →	-0.904	-1.422	<.001	<.001	3	4
GBM	TCF20_S574 →	+0.398	+0.474	<.001	<.001	3	4
LSCC	RACGAP1 →	+0.564	+0.553	<.001	<.001	3	4
BRCA	NUP50 →	+0.292	+1.395	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,557 associations by consensus.

Exploration

HMGB1P10 survival (RNA) · tumor vs normal (RNA) · all HMGB1P10 data types