HMGB1P1

Across TCGA patient cohorts, HMGB1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,904 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGB1P1-associated proteins across cancer lineages are BAZ1B_S349, ULK1_S469, and NONO_T450. Each is linked with HMGB1P1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P1-to-partner and partner-to-HMGB1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P1 versus BAZ1B_S349 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P1→partner) and Y-score (partner→HMGB1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BAZ1B_S349 →	+1.024	+1.630	<.001	.004	3	3
OV	ULK1_S469 →	+0.770	+2.647	<.001	<.001	3	3
BRCA	NONO_T450 →	+0.339	+1.321	.003	.004	3	3
UCEC	HMGCL →	-0.416	-0.799	.004	.009	3	3
OV	ZBTB21_S435 →	+1.012	+1.606	<.001	.002	3	3
BRCA	ZNF638_S508 →	+0.302	+1.453	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,904 associations by consensus.

HMGB1P1 vs BAZ1B_S349 — BRCA

Explore this scatter interactively →