HMGA1P6

Across TCGA patient cohorts, HMGA1P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,088 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HMGA1P6-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Interstrand cross-link repair, and Spindle elongation. Each is linked with HMGA1P6 in more than 12 cancer types. Because this analysis shows association rather than direction, both HMGA1P6-to-partner and partner-to-HMGA1P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by HMGA1P6-low versus HMGA1P6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGA1P6→partner) and Y-score (partner→HMGA1P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA replication checkpoint signaling →	+0.064	+0.152	<.001	<.001	3	13
STAD	Interstrand cross-link repair →	+0.039	+0.126	<.001	<.001	3	12
SARC	Spindle elongation →	+0.082	+0.023	.005	.008	2	13
STAD	DNA replication initiation →	+0.060	+0.179	<.001	<.001	3	12
STAD	Cell cycle checkpoint signaling →	+0.049	+0.111	<.001	<.001	3	12
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.048	+0.109	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,088 associations by consensus.

DNA replication checkpoint signaling by HMGA1P6 expression — STAD

Explore this box plot interactively →