HMGA1P5

Across TCGA pan-cancer cohorts, HMGA1P5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated HMGA1P5 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher HMGA1P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGA1P5 expression acts as an unfavorable survival marker, although some lineages such as UCS and UVM show a favorable association.

BLCA, UCS, and ACC are the cancer types where HMGA1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	IV	0.240	0.512	.001	77	view →
UCS	OS	Median	III,IV	0.551	0.194	.005	68	view →
ACC	OS	Tertile	All	0.218	0.677	.001	45	view →
UVM	DFS	Tertile	All	0.767	0.487	.005	42	view →
UCEC	OS	Tertile	IV	0.713	0.292	<.001	36	view →
KIRC	DFS	Tertile	III,IV	0.228	0.544	.001	33	view →
LUSC	DFS	Median	All	0.334	0.453	.008	18	view →
CHOL	OS	Tertile	II,III,IV	0.201	0.700	.036	18	view →
LIHC	DFS	Tertile	III,IV	0.146	0.365	.007	18	view →
HNSC	DFS	Tertile	IV	0.465	0.160	.022	15	view →
READ	OS	Tertile	All	0.980	0.866	.013	8	view →
PRAD	OS	Quartile	All	0.982	0.997	.005	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

HMGA1P5–BLCA (DFS)

Open the BLCA breakdown →