HMCN2

Across TCGA patient cohorts, HMCN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,481 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HMCN2-associated proteins across cancer lineages are CAVIN1, KANK2, and PGM5. Each is linked with HMCN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMCN2-to-partner and partner-to-HMCN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMCN2 versus CAVIN1 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMCN2→partner) and Y-score (partner→HMCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAVIN1 →	+0.835	+0.360	<.001	.006	3	8
UCEC	KANK2 →	+0.732	+0.462	<.001	<.001	3	8
HNSC	PGM5 →	+0.981	+0.685	<.001	<.001	3	8
UCEC	TLN1 →	+0.472	+0.477	<.001	<.001	3	8
CCRCC	CNN1 →	+1.344	+0.678	<.001	<.001	3	7
UCEC	CNRIP1 →	+0.757	+0.490	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,481 associations by consensus.

HMCN2 vs CAVIN1 — BRCA

Explore this scatter interactively →