HMCN2

Across TCGA patient cohorts, HMCN2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,616 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HMCN2-associated genes across cancer lineages are KANK3, JAM2, and FAM162B. Each is linked with HMCN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMCN2-to-partner and partner-to-HMCN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMCN2 versus KANK3 in CCRCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMCN2→partner) and Y-score (partner→HMCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KANK3 →	+1.147	+0.684	.001	.002	3	5
UCEC	JAM2 →	+1.070	+0.677	<.001	<.001	3	5
CCRCC	FAM162B →	+1.394	+0.771	<.001	.002	3	5
CCRCC	CCL21 →	+1.996	+0.693	<.001	<.001	3	4
CCRCC	EGFL7 →	+0.767	+0.531	<.001	<.001	3	4
LSCC	CDH5 →	+0.658	+0.619	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,616 associations by consensus.

HMCN2 vs KANK3 — CCRCC

Explore this scatter interactively →