HMCN2

Across TCGA cell cohorts, HMCN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,430 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HMCN2-associated GO terms across cancer lineages are L-arginine biosynthetic process, Cellular response to ammonium ion, and Response to mycotoxin. Each is linked with HMCN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMCN2-to-partner and partner-to-HMCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-arginine biosynthetic process grouped by HMCN2-low versus HMCN2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMCN2→partner) and Y-score (partner→HMCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	L-arginine biosynthetic process →	+0.220	+1.184	<.001	<.001	3	7
OVARY	Cellular response to ammonium ion →	+0.753	+0.162	.002	.006	2	8
LUNG_NSCLC_LUAD	Response to mycotoxin →	+0.516	+0.294	.003	.008	3	7
SOFT_TISSUE	Cellular response to oleic acid →	+0.614	+1.684	.009	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Vascular endothelial growth factor receptor-2 signaling pathway →	+0.135	+0.286	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of viral transcription →	+0.102	+0.701	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,430 associations by consensus.

L-arginine biosynthetic process by HMCN2 expression — SOFT_TISSUE

Explore this box plot interactively →