HMCN1

Across TCGA cell cohorts, HMCN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,549 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HMCN1-associated GO terms across cancer lineages are Protein-containing complex disassembly, Protein localization to nucleus, and Cytoskeleton-dependent intracellular transport. Each is linked with HMCN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HMCN1-to-partner and partner-to-HMCN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-containing complex disassembly grouped by HMCN1-low versus HMCN1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMCN1→partner) and Y-score (partner→HMCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein-containing complex disassembly →	+0.074	+1.884	.002	.008	3	9
STOMACH	Protein localization to nucleus →	+0.059	+2.223	<.001	.001	3	9
SKIN	Cytoskeleton-dependent intracellular transport →	+0.035	+2.515	.001	.001	3	9
STOMACH	Negative regulation of myoblast fusion →	+0.149	+2.090	.001	.003	3	9
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.146	+1.988	.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of platelet-derived growth factor receptor signaling pathway →	+0.183	+1.630	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

Protein-containing complex disassembly by HMCN1 expression — STOMACH

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