HLX

Across TCGA patient cohorts, HLX RNA expression is significantly associated with the protein abundance of many other proteins, with 20,651 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HLX-associated proteins across cancer lineages are PRKG1, F13A1, and RSU1. Each is linked with HLX in more than 8 cancer types. Because this analysis shows association rather than direction, both HLX-to-partner and partner-to-HLX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HLX versus PRKG1 in OV, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLX→partner) and Y-score (partner→HLX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRKG1 →	+0.781	+0.508	<.001	<.001	3	9
GBM	F13A1 →	+0.791	+0.523	<.001	<.001	3	9
OV	RSU1 →	+0.387	+0.420	<.001	<.001	3	8
OV	SERPING1 →	+0.593	+0.422	<.001	<.001	3	8
COAD	ILK →	+0.456	+0.378	<.001	.001	3	8
OV	ITGA5 →	+0.583	+0.452	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,651 associations by consensus.

HLX vs PRKG1 — OV

Explore this scatter interactively →