HLF

Across TCGA cell cohorts, HLF RNA expression is significantly associated with the RNA expression of many other genes, with 5,308 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HLF-associated genes across cancer lineages are TSPAN7, TMEM63C, and CIPC. Each is linked with HLF in more than 4 cancer types. Because this analysis shows association rather than direction, both HLF-to-partner and partner-to-HLF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HLF versus TSPAN7 in LUNG_SCLC, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLF→partner) and Y-score (partner→HLF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TSPAN7 →	+2.238	+1.380	<.001	<.001	3	4
BREAST	TMEM63C →	+2.025	+1.100	<.001	<.001	3	4
LUNG_SCLC	CIPC →	+0.898	+1.350	<.001	.001	3	4
LIVER	OVGP1 →	+1.401	+1.876	<.001	<.001	2	5
BREAST	REEP1 →	+1.970	+1.131	<.001	<.001	3	4
SOFT_TISSUE	BVES →	+1.960	+0.878	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,308 associations by consensus.

HLF vs TSPAN7 — LUNG_SCLC

Explore this scatter interactively →