HLA-F

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HLA-F RNA expression is significantly associated with the go_rna of many other GO terms, with 4,977 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HLA-F-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous antigen, Antigen processing and presentation of endogenous peptide antigen via MHC class I, and Antigen processing and presentation of endogenous peptide antigen. Each is linked with HLA-F in more than 19 cancer types. Because this analysis shows association rather than direction, both HLA-F-to-partner and partner-to-HLA-F results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-F→partner) and Y-score (partner→HLA-F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTAntigen processing and presentation of endogenous antigen →+0.249+2.415<.001<.001320
OESOPHAGUSAntigen processing and presentation of endogenous peptide antigen via MHC class I →+0.330+3.827<.001<.001320
OESOPHAGUSAntigen processing and presentation of endogenous peptide antigen →+0.327+3.827<.001<.001320
LUNG_NSCLC_LUSCAntigen processing and presentation of peptide antigen via MHC class I →+0.244+3.772<.001<.001319
LUNG_NSCLC_LUADPositive regulation of CD8-positive, alpha-beta T cell proliferation →+0.260+2.279.007<.001318
OESOPHAGUSNegative regulation of response to biotic stimulus →+0.105+3.545.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,977 associations by consensus.

Exploration