Across TCGA patient cohorts, HLA-DQB1-AS1 RNA expression is significantly associated with the RNA expression of many other genes, with 13,929 significant associations in total. UVM shows the largest number of these associations.

The most reproducible HLA-DQB1-AS1-associated genes across cancer lineages are HLA-DPB1, HLA-DPA1, and HLA-DMB. Each is linked with HLA-DQB1-AS1 in more than 32 cancer types. Because this analysis shows association rather than direction, both HLA-DQB1-AS1-to-partner and partner-to-HLA-DQB1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DQB1-AS1→partner) and Y-score (partner→HLA-DQB1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	HLA-DPB1 →	+2.290	+1.679	<.001	<.001	3	33
BLCA	HLA-DPA1 →	+2.549	+1.686	<.001	<.001	3	33
UCS	HLA-DMB →	+2.148	+1.297	<.001	<.001	3	33
LAML	HLA-DQB1 →	+3.118	+2.926	<.001	<.001	3	33
SKCM	CIITA →	+1.945	+1.779	<.001	<.001	3	33
UCS	CD74 →	+2.457	+1.310	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,929 associations by consensus.

Exploration

HLA-DQB1-AS1 survival (RNA) · tumor vs normal (RNA) · all HLA-DQB1-AS1 data types