Across TCGA patient cohorts, HLA-DQB1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HLA-DQB1-AS1-associated proteins across cancer lineages are HLA-DPB1, HLA-DQB1, and CD4. Each is linked with HLA-DQB1-AS1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HLA-DQB1-AS1-to-partner and partner-to-HLA-DQB1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DQB1-AS1→partner) and Y-score (partner→HLA-DQB1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HLA-DPB1 →	+0.889	+1.173	<.001	<.001	3	10
UCEC	HLA-DQB1 →	+1.098	+1.160	<.001	<.001	3	10
LSCC	CD4 →	+0.673	+1.091	<.001	<.001	3	9
GBM	HLA-DPA1 →	+0.703	+0.758	<.001	<.001	3	9
LSCC	LCP2 →	+0.500	+1.021	<.001	<.001	3	9
GBM	LPXN →	+0.588	+1.052	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,991 associations by consensus.

Exploration

HLA-DQB1-AS1 survival (RNA) · tumor vs normal (RNA) · all HLA-DQB1-AS1 data types