HLA-DQA1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HLA-DQA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HLA-DQA1-associated proteins across cancer lineages are WAS, WDFY4, and CSK. Each is linked with HLA-DQA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HLA-DQA1-to-partner and partner-to-HLA-DQA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HLA-DQA1→partner) and Y-score (partner→HLA-DQA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWAS →+0.533+1.360<.001<.001310
OVWDFY4 →+0.643+1.749<.001<.001310
OVCSK →+0.360+1.245<.001<.001310
OVCYRIB →+0.432+1.787<.001<.001310
OVDEF6 →+0.585+2.090<.001<.001310
UCECDOCK10 →+0.512+0.995<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,350 associations by consensus.

Exploration