HK3

Across TCGA patient cohorts, HK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,471 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HK3-associated proteins across cancer lineages are SKAP2, STK10, and THEMIS2_T593. Each is linked with HK3 in more than 9 cancer types. Because this analysis shows association rather than direction, both HK3-to-partner and partner-to-HK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK3 versus SKAP2 in GBM, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HK3→partner) and Y-score (partner→HK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SKAP2 →	+0.840	+1.542	<.001	<.001	3	10
UCEC	STK10 →	+0.386	+1.200	<.001	.002	3	10
OV	THEMIS2_T593 →	+1.380	+1.141	<.001	.001	3	10
OV	TNFAIP8L2 →	+0.800	+1.028	<.001	.001	3	10
GBM	WAS →	+0.731	+1.611	<.001	<.001	3	10
OV	WDFY4 →	+0.650	+1.473	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,471 associations by consensus.

HK3 vs SKAP2 — GBM

Explore this scatter interactively →